Like most herbs, cannabis does have some antimicrobial and immune-boosting properties, but it is not as strong an antimicrobial as many other herbs. There are many better herbal choices for overcoming chronic Lyme disease and similar conditions related to chronic infections with stealth microbes such as fibromyalgia and chronic fatigue syndrome. (Top ones include andrographis, berberine, cat’s claw, Japanese knotweed, sarsaparilla, and garlic.)
The few CBD studies out there give us limited information, and hardly any about recreational CBD use. One study gave people different amounts of ingested CBD (100, 300, and 900 mg), as well as, for comparison, a placebo and Klonopin; those people then had to give a public speech, an action associated with high levels of anxiety in the broad populace. Neither 100 mg nor 900 mg, nor the placebo, had any effect. The 300 mg dose, though, did have a measurable calming effect on heart rate, blood pressure, and anxiety. (The Klonopin also worked.)
If CBD-dominant products alone are not enough to treat a particular case, products with a higher ratio of THC are sometimes recommended to better manage pain. For day use, more stimulating, sativa varieties with higher concentrations of myrcene could be added to the formula. In general, for pain, and especially for evening and nighttime, indica strains are favored for their relaxing, sedative effect. A person without experience with THC should use caution and titrate slowly up to higher doses. Research as well as patient feedback have indicated that, in general, a ratio of 4:1 CBD:THC is the most effective for both neuropathic and inflammatory pain. Each individual is different, however—for some, a 1:1 ratio of CBD:THC can be more effective, and others prefer a high-THC strain when it can be tolerated. Each patient’s tolerance and sensitivity will differ, and through titration the correct strain and ratio combination can be found.
Sativex, an oral spray containing both CBD and THC, can treat MS-induced pain. During one study, researchers gave Sativex to 47 participants with MS. Results were largely positive. Patients who used this spray felt notably better. Their muscle and walking spasms decreased, and they felt pain relief. Thanks to studies such as this one, several countries approved using Sativex in MS treatment.
In 2016, the Drug Enforcement Agency (DEA) created a new coding category to classify “marihuana extracts” like CBD, but in doing so made clear that CBD was still classified as a Schedule I drug and therefore still illegal. Although the 2018 FDA approval of Epidiolex meant that the DEA removed this specific CBD drug from Schedule I classification, all other non-FDA approved forms for CBD remained classified as Schedule I drugs.
It should be noted that recreational use of marijuana (high THC, low CBD cannabis) does result in dependence (but different from narcotics or alcohol, and not as debilitating). Chronic use of THC may be associated with atrophy in certain areas of the brain and reduction of certain cognitive functions (at this point, studies are not conclusive). Interestingly, studies have shown that taking CBD oil regularly can restore areas of the brain that have become atrophied in marijuana abusers.
Still, CBD presents other risks for false positives. "If people are using CBD products that don't have a CoA (Certificate of Analysis) that indicates zero THC, THC could show up on a drug screen," Okel says. Availability of CBD oil has exploded, but it's not a well-regulated industry. Some oils that claim to be pure CBD have some sneaky THC in there, and that could mess up a drug test. Okel advises everyone to only purchase CBD oils with CoA purity guarantee to avoid ingesting trace amounts of THC.
The body of research on cannabidiol, CBD oil benefits, THC, and other cannabinoids has grown exponentially in the past decade. The following brings together the latest scientific studies and stories from patients and doctors with advice on treating specific symptoms. It also includes dosage suggestions and information on recommended types of cannabinoid-based medicines for the particular condition.
Answering the question “what is CBD oil” would be incomplete without mentioning the many CBD oil benefits. In addition to positively affecting the endocannabinoid system, CBD has been the focus of more than 23,000 published studies about cannabinoids in relation to various medical indications including anxiety, epilepsy, inflammation, cancer and chronic pain to name few. You can even find CBD for pets that is specially formulated to safely allow your pets to experience the natural benefits of CBD. For a more comprehensive look at these and other studies, visit our medical research and education page.
When considering our different dietary hemp products, know that they all come in two strengths. Our Original Hemp blends (Hemp Classic, Hemp Complete, & Signature Blend) all have 250+mg of cannabinoids per fluid ounce, and our concentrated blends have 1,500+mg per fluid ounce, six times the potency of our traditional oils. We’ve found that sometimes less is more, but nevertheless, some people like to take very large serving sizes of our hemp extracts.
Let’s take a good look at the claim, which is based upon the underlying premise that hemp acts as phyto-remediator. Well, yes, it does. All cannabis serves exceptionally well for phyto-remedation purposes. This means that cannabis mops up contamination and can be used to clean up all manner of nastiness. It also means that if it’s grown under less-than-pristine conditions, it carries that nastiness with it when it’s harvested. And, it carries that nastiness with it into products made with it. So, clean sourcing is an especially big deal with ALL cannabis.
Kent, My mother has suffered from severe migraines since she was a child. Six weeks ago, she received the hemp oil tincture (I do not know what dosage). She does not take it daily. She rubs a drop or two on her temples at the start of a migraine. The drops worked more effectively for her than her medication did, and now that is all she uses. Hope this helps.
Some individuals have been found to have mutations on the CNR1 gene, which is responsible for coding the CB1 receptor (a type of receptor in cells throughout your body that interacts with cannabinoids). Issues with the CNR1 gene can ultimately result in a poorly functioning endocannabinoid system, which is an important variable when figuring out how to use CBD oil.
Cannabidiol (CBD) is one of dozens of non-psychoactive cannabinoids found in the hemp plant. Cannabidiol, and all the other cannabinoids, were patented by the United States Government in 2003 as neuroprotectants and antioxidants (Patent No. 6,630,507). Cannabinoids are characterized by their ability to act on the cannabinoid receptors that are found throughout the body. CBD and other cannabinoids are naturally occurring compounds that display potent anti-inflammatory and pain-relieving properties. They can promote the body’s healthy regulation of the central nervous, immune, and endocannabinoid systems.
Note that the original federal distinction between hemp and marijuana in the Controlled Substances Act of 1970 was intended to separate useful industrial applications of hemp from the potentially hazardous smoking or other consumption of marijuana and its constituents for recreational purposes. In the fine print of the Controlled Substances Act however, exemption of hemp from the definition of marijuana did not include the resin extracted from the mature stalks of plants which might be expected to contain concentrated cannabinoids. While the 2018 Farm Bill passed by a Republican majority US Senate and House of Representatives in order to provide relief to farmers so that they can now grow hemp for industrial applications and apply for grants and insurance to do so, it may not have been intended to provide a new pathway to extract and purify CBD from hemp plants with the intent of large-scale human consumption as a food additive, dietary supplement, or medication. But make no mistake — cannabis companies are excited about and are intending to negotiate just this possibility. We’ll have to see how the FDA and DEA, and in turn federal judges and legislators, respond.
Third party laboratories analyze all of our full-spectrum hemp extracts and supplements for cannabinoid potency, heavy metals, bacterial/microbial life, mycotoxins (fungus), and pesticides. Our isolate is tested for potency, heavy metals, and pesticides. The unsummarized results of testing for all produced batches can be found in our online batch database.
The mosaic of laws that govern CBD legality across the globe varies just as much as the legislation across the US. Generally, CBD extract is legal in most countries, but what makes it illegal is where and what it’s extracted from. Most Group of 20 (G20) countries allow CBD extracted from industrial hemp, but not CBD extracted from whole-plant marijuana. Note, however, the differences between the two. Legislation regarding international travel with CBD also varies among countries. For the foreseeable future, the best practice would be to search online, or contact the respective embassies or consulates, before traveling to determine whether your CBD is safe and legal.