These mounting developments in the elicited a problem amongst cannabis cultivators across the US: decades of selectively breeding cannabis to achieve the maximum amount of THC for a strong high reduced the overall preponderance of CBD in cultivars across the country to trace lows. Essentially, CBD had been selectively bred out of existence across the country.

Both Bonn-Miller and Ward stress that it's up to the consumer to be well-educated about the material they're purchasing and the research that's out there. "The companies that are creating [cannabis oils] are offering lots of claims about its use that are not necessarily substantiated by any research," Bonn-Miller said. So "I think there needs to be, from a consumer standpoint, a lot of vigilance," he added.
Insomnia: The anxiety-alleviating and sleep-prolonging qualities of CBD oil make it a good option for many people with insomnia. Those who experience insomnia due to pain or discomfort may also find that using CBD oil alleviates their physical symptoms to a noticeable extent. CBD oil may also promote daytime wakefulness when taken in small amounts; people with insomnia can use it as a pick-me-up if they feel excessively tired due to lack of restful sleep.
However, Bonn-Miller told Live Science that he thinks cannabis research is on the upswing. "If we flash forward five years I think you'll see more studies," he said. Those studies could reveal more conditions that CBD may be helpful for and may also reveal that some of the reasons why people say they use CBD oil are not supported by the science but are instead a placebo effect. "And that's why we need to do the studies," he said.  
Keep in mind that CBD levels may vary from crop to crop—even from plant to plant. However, below are some strains that have been bred to contain higher CBD levels, so they might be a good place to start. Check the map on their strain page to see if these are sold at a dispensary near you. We also recommend checking with dispensaries about the specifics of their strains’ CBD levels. It’s always a good idea to purchase only lab-tested products that clearly state the CBD/THC levels so you know what kind of experience to expect.
In the United States, over three million people suffer from epilepsy – 470,000 of those people are children. Epilepsy is a disorder of the brain that causes seizures – of which there are over thirty different kinds, ranging from mild and infrequent to life-threatening. Not surprisingly, people with epilepsy face significant challenges – from the cost of healthcare to work limitations and social isolation.
[387] S. Maione, F. Piscitelli, L. Gatta, D. Vita, L. De Petrocellis, E. Palazzo, V. de Novellis, and V. Di Marzo, “Non-psychoactive Cannabinoids Modulate the Descending Pathway of Antinociception in Anaesthetized Rats through Several Mechanisms of Action,” British Journal of Phramacology 162, no. 3 (2011): 584. doi:10.1111/j.1476-5381.2010.01063.x.
Definitely not. Standard hemp oil, which can be found very cheaply at a grocery store, is a much different product than our full spectrum hemp extracts (not from seed). Standard hemp oil is produced by cold pressing the seeds, whereas our hemp extract is a full plant extraction with many components not typically found in the seeds. Hemp seed oil is considered to be a great nutritive food, but it doesn’t have the naturally occurring terpenes, cannabinoids and other components that our extracts do have.
CBD oil alleviates physical pain and anxiety – both of which can have a negative impact on sleep. Additionally, CBD oil can actually prolong sleep for some, leading to more rest from night to night. Most medical experts agree that marijuana is not particularly beneficial for individuals with medical conditions and/or mental health disorders, as the THC can increase their symptoms; this makes CBD oil a good alternative option for people with the following sleep disorders and medical conditions.

Pharmacists have since moved to metric measurements, with a drop being rounded to exactly 0.05 mL (50 μL, that is, 20 drops per milliliter) - https://en.wikipedia.org/wiki/Drop_(unit)1oz is 30 mL1000mg/30mL = 33.3 mg/mL CBD concentration20 drops * .05 mL/drop = 1mL10 drops * .05 mL/drop = .5mLyou take 33.3 mg in the morning and 16.65mg at nightI might suggest taking 50mg in the morning: 50mg / 33.3 mg/mL = 1.50 mL 30 dropstry it for a couple days and see how it helps


If your looking for specialty products to help the pet in your family feel better then Elixinol™ CBD Pet Treats can help. Our latest CBD hemp dog treats deliver more dog treat contains 3 milligrams of CBD in every treat! Available in 4 pet-friendly flavors plus they come in larger sizes for large breed dogs who want more cannabidiol goodness! All pet treats are natural and tested by 3rd party laboratories to ensure the safety and efficacy. Elixinol™ CBD Pet Treats have has been specially formulated for canines.
Cannabidiol, or CBD for short, is a natural phyto-cannabinoid (or plant-based chemical compound) found in cannabis plants, including hemp and marijuana. Unlike other cannabinoids — namely tetrahydrocannabinol, or THC — CBD does not produce any psychoactive effects, and will actually counteract these effects to a degree. CBD will induce feelings of sleepiness; for this reason, it can be an effective soporific for people who struggle to fall and/or remain asleep due to insomnia and other sleep disorders.
NuLeaf Naturals is headquartered in Colorado, but we ship anywhere in the US. All of our organic CBD oil products will be sent to you via USPS, FedEx, or UPS and should arrive in just 2-3 business days. We offer special pricing options for bulk orders. If you sell health and wellness products and would be interested in promoting medical cannabis oil, consider becoming a wholesale CBD oil partner with us.

With the increasing hype surrounding CBD, some — including this author — have speculated that it will become the next health fad, like taking fish oil or opting for a gluten-free diet, whether or not the research to support far-reaching health benefit claims pans out (see this recent New York Times op-ed by Cornell Medical College psychiatrist Richard Friedman urging caution). “Big Beverage” companies like Coca-Cola have even been exploring whether they should jump in the ring lest they miss out, bringing CBD infused drinks to the mass market sometime in the not-too-distant future (see my blogpost "Coca, Cola, and Cannabis: Psychoactive Drugs as Beverages").

Sufferers of chronic pain owe it themselves to try this product. CBD oil has been a God sent miracle. I suffer from nerve/muscle pain from my L5/S1 disc being in my spinal canal instead of between the vertebrae. For 5 years I limited my activities down to almost nothing to avoid pain. At 35, being a runner/road cyclist that was very active and in great shape, that was devastating not only to my fitness level but also my emotional and mental state. Opioids did nothing for the pain and just produced unwanted side effects. About a month or two ago, a friend got me to try pure CBD oil and within 2 days I was able to tell a difference. No shooting pains down my back/butt/leg/foot. Less muscle cramping and discomfort. The only side effect Ive had so far has been softer bowel movements and I notice I go twice a day instead of once. Ill take that over liver issues/constipation/etc with pharmaceutical company drugs every time. I was able to do yard work back to back days without issue. I was able to go bowling and shopping for hours walking around without consequence. Ive been taking it daily, three times a day (anywhere from 0.25ml to 0.5ml each dose) and it keeps me 90% pain free. I rediscovered my mouth was capable of a smile instead of a grimace. This oil doesnt cure my affliction as it treats symptoms of pain/inflammation but its given me my life back. Im grateful every single day for this product!

Cannabidiol, or CBD for short, is a natural phyto-cannabinoid (or plant-based chemical compound) found in cannabis plants, including hemp and marijuana. Unlike other cannabinoids — namely tetrahydrocannabinol, or THC — CBD does not produce any psychoactive effects, and will actually counteract these effects to a degree. CBD will induce feelings of sleepiness; for this reason, it can be an effective soporific for people who struggle to fall and/or remain asleep due to insomnia and other sleep disorders.

Cannabidiol, or CBD for short, is a natural phyto-cannabinoid (or plant-based chemical compound) found in cannabis plants, including hemp and marijuana. Unlike other cannabinoids — namely tetrahydrocannabinol, or THC — CBD does not produce any psychoactive effects, and will actually counteract these effects to a degree. CBD will induce feelings of sleepiness; for this reason, it can be an effective soporific for people who struggle to fall and/or remain asleep due to insomnia and other sleep disorders.
Without a doubt, cancer is one of the worst diseases. There are various treatments for it, and all of them vary in how effective they are. CBD oil, on the other hand, shows promise when it comes to reducing cancer symptoms. Not only that, but proper use of CBD oil can help with cancer treatment side effects, such as vomiting, nausea, and excessive pain. Did you know that CBD oil helps with loss of appetite?

Always start with the micro dose to test sensitivity and go up as needed within the dosing range, before going to the next, until symptoms subside. The micro to standard dose is usually recommended to treat stress and anxiety with CBD. For relief of immediate symptoms, as in a panic or anxiety attack, vaporizing or smoking work well. The medication lasts one to three hours, whereas most ingested products, including CBD oil, take thirty to sixty minutes before taking effect and last six to eight hours. Vaporizers that use a cartridge filled with the CO2 concentrate are highly effective, and these are available in various ratios of CBD to THC. Herbal vaporizers that use the whole plant are also an effective delivery method. Sublingual sprays or tinctures taken as liquid drops take effect quickly and last longer than inhaled products.
A CNN program that featured Charlotte's Web cannabis in 2013 brought increased attention to the use of CBD in the treatment of seizure disorders.[66][67] Since then, 16 states have passed laws to allow the use of CBD products with a doctor's recommendation (instead of a prescription) for treatment of certain medical conditions.[68] This is in addition to the 30 states that have passed comprehensive medical cannabis laws, which allow for the use of cannabis products with no restrictions on THC content.[68] Of these 30 states, eight have legalized the use and sale of cannabis products without requirement for a doctor's recommendation.[68]

Note that the federal definition of hemp requires that it contain less than 0.3% delta-9-tetrahydrocannabinol (THC), the euphorigenic component of cannabis. And while the terms “cannabis” and “marijuana” are often used interchangeably, the Controlled Substances Act of 1970 specifically excluded the mature stalks of the cannabis plant used in industrial applications — essentially hemp — from its definition of marijuana.


For this study, 24 people with social anxiety disorder received either 600 milligrams (mg) of CBD or a placebo an hour and a half before performing a simulated public speaking test. Additionally, 12 other people with social anxiety disorder performed the same test without receiving any CBD treatment. Results revealed that pre-treatment with CBD significantly reduced anxiety, cognitive impairment, and discomfort while participants were delivering their speech.
CBD primarily interacts with the body’s endocannabinoid system, a grouping of millions of cannabinoid receptors found throughout your body, but are primarily clustered in the brain and central nervous system. While CBD is a phytocannabinoid, or plant-based cannabinoid, your body also naturally produces cannabinoids, known as endocannabinoids. Almost every organ of your body, including your skin and digestive tract, contains cannabinoid receptors. The endocannabinoid system has four primary purposes including neuroprotection, stress relief, immune response, and regulating the body’s general state of balance, impacting faculties such as appetite, sleep, mood, and pain.
It should be noted that recreational use of marijuana (high THC, low CBD cannabis) does result in dependence (but different from narcotics or alcohol, and not as debilitating). Chronic use of THC may be associated with atrophy in certain areas of the brain and reduction of certain cognitive functions (at this point, studies are not conclusive). Interestingly, studies have shown that taking CBD oil regularly can restore areas of the brain that have become atrophied in marijuana abusers.
CBD is short for cannabidiol, and it is one of more than 60 compounds found in these plants.  It acts on the body’s endocannabinoid system, creating physical changes in the body, which can be beneficial in many ways.  In recent times, it has become increasingly understood that taking CBD oil, a product made from CBD, can have a positive influence on many aspects of life and health.
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Infusions: Research and opportunity have driven chefs and chemists to infuse CBD into all sorts of readily usable products, such as edibles to elixirs, sublingual sprays, capsules and even topicals. Much like concentrates, each infusion sports specific combinations or isolations of CBD, THC, and other cannabinoids, allowing users to pick and choose products that suit their exact needs. CBD topicals, for example, are incredibly effective when applied to surface-level problems like bruises, joint aches, and headaches, and have been scientifically proven to successfully combat skin-based issues including pruritus with far broader implications.
Despite this, CBD is something nobody knows much about, and certainly nobody is monitoring it properly. CBD is widely marketed as a supplement, despite the Food and Drug Administration saying it does not qualify as such (this is because it is an active ingredient in drugs which are either approved or under investigation to be approved). According to the FDA, the 2018 farm bill “preserved the agency’s current authority to regulate products containing cannabis or cannabis-derived compounds,” though the agency has largely ignored CBD up until now. On the FDA’s FAQ page, a vague answer maintains there are “many factors in deciding whether or not to initiate an enforcement action”; the agency plans to hold a public meeting and generally fact-gather “in the near future.” The Department of Agriculture handles research grants and pilot programs for hemp, but that’s where its involvement ends.
The oral use of cannabis and CBD for anxiety appears in a Vedic text dated around 2000 BCE,[238] and it is one of the most common uses of the plant across various cultures. While THC can increase anxiety in some patients, it lowers it in others. However, CBD effects have been shown to consistently reduce anxiety when present in higher concentrations in the cannabis plant. On its own, CBD has been shown in a number of animal and human studies to lessen anxiety. The stress-reducing effect appears to be related to activity in both the limbic and paralimbic brain areas.
I have been diagnosed with endometriosis and several bulging disk. The amount of pain from both because of all the inflammation had been unbearable. Pain meds aleve and several medications that were supposed to help failed me. I went from not doing anything to waking up in the morning like a new woman I never thought this would work Im in tears about how great I feel. Give it a try my family is in complete disbelief that I went from a 97 year old woman their description lol to my 32 yr old self. Life changing is TRUE
Cannabidiol, or CBD, is one of more than 60 cannabinoid compounds found in a marijuana plant, which includes the substance most commonly associated with the “stoned” effect, THC (tetrahydrocannabinol). CBD is legal, to varying degrees, in 46 states. New York legalized it in 2014, in part due to the efforts of Gov. Andrew Cuomo, who argued at the time that it would be a mistake to outlaw the substance that had been shown to be one of the few ways of treating cases of medication-resistant childhood epilepsy. (He also viewed the hemp industry as a way to bring new jobs to the economically hard-hit Southern Tier region.)
Hi Colleen, it's almost a year later and I'm wondering how you're doing. I'm experiencing a recurrence of Stage 3 ovarian, originally diagnosed in 2011. I've decided to get some chemo, not sold on another 6 cycles though. As a new MMJ patient, I'm still going to go through with Rick Simpson Oil (THC+CBD,) and I just joined a program with my local dispensary to get CBD capsules for $2 each when I order them at least 30 at a time. I hope you're doing well!! I'm off to do more research on dosing. **NOTE: If you have ANY experience with CBD treatment of ovarian cancer, PLEASE respond. Thank you!!
Because our hemp extract is a natural supplement that comes from a plant, it has a taste that some consider to be bitter and strong. While many of our customers like the flavor, some would rather find a way to mask it. If that’s you, try mixing the oil in honey, applesauce, or a smoothie. Another great option is to try our hemp extract in capsule form. These are easy to swallow with a glass of water or your favorite juice.
Derived from the stalk and seed of cannabis (hemp) plants, cannabidiol (CBD) oil or CBD hemp oil is a natural botanical concentrate that is high in the compound CBD. Of the more than 85 cannabinoids so far identified in the cannabis plant, CBD is the second most common after tetrahydrocannabinol (THC). Unlike THC, CBD is non-psychotropic and therefore doesn’t cause a euphoric high.
Cannabidiol, or CBD for short, is a natural phyto-cannabinoid (or plant-based chemical compound) found in cannabis plants, including hemp and marijuana. Unlike other cannabinoids — namely tetrahydrocannabinol, or THC — CBD does not produce any psychoactive effects, and will actually counteract these effects to a degree. CBD will induce feelings of sleepiness; for this reason, it can be an effective soporific for people who struggle to fall and/or remain asleep due to insomnia and other sleep disorders.

Kimberly is the reference editor for Live Science and Space.com. She has a bachelor's degree in marine biology from Texas A&M University, a master's degree in biology from Southeastern Louisiana University and a graduate certificate in science communication from the University of California, Santa Cruz. Her favorite stories include animals and obscurities. A Texas native, Kim now lives in a California redwood forest. You can follow her on Twitter @kimdhickok.
CBD does not appear to have any psychotropic ("high") effects such as those caused by ∆9-THC in marijuana, but may have anti-anxiety and anti-psychotic effects.[9] As the legal landscape and understanding about the differences in medical cannabinoids unfolds, it will be increasingly important to distinguish "medical marijuana" (with varying degrees of psychotropic effects and deficits in executive function) – from "medical CBD therapies” which would commonly present as having a reduced or non-psychoactive side-effect profile.[9][58] 

While researchers are calling for more robust studies on the role of CBD on mood disorders, there is promising research that points to CBD’s role as an anxiolytic – which means it has anti-anxiety effects. Another study showed CBD to have antidepressant effects comparable to those of the prescription antidepressant Imipramine. We noted above that CBD increases levels of glutamate and serotonin – and it’s these same neurotransmitters that play a crucial role in mood regulation.
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