You move fast, train hard, and recover the best that you can. Whether an athlete, government employee, or working professional that prefers the least amounts of THC in your CBD oil – our X-Oil was made with you in mind. It contains only the barest of trace amounts of THC, for ultimate confidence and effectiveness, so you can focus on performing at the top level.The first-ever CBD oil compliant with worldwide regulations brought to you by HempMeds. It’s ahead of the curve, just like you want to be.
^ Hayakawa K, Mishima K, Nozako M, Ogata A, Hazekawa M, Liu AX, Fujioka M, Abe K, Hasebe N, Egashira N, Iwasaki K, Fujiwara M (March 2007). "Repeated treatment with cannabidiol but not Delta9-tetrahydrocannabinol has a neuroprotective effect without the development of tolerance". Neuropharmacology. 52 (4): 1079–87. doi:10.1016/j.neuropharm.2006.11.005. PMID 17320118.
Cannabidiol (CBD) is a naturally-occurring constituent of industrial hemp (cannabis sativa) plants. It is the most abundant non-psychoactive cannabinoid found in cannabis and is being scientifically investigated for numerous reasons. Most people have heard of a cannabinoid called THC, which is the ingredient in cannabis that gets users high. Unlike THC, CBD (cannabidiol) is a non-psychoactive cannabinoid and does not cause a high.
First, let’s look at the differences between the plants that make CBD oil.  To start with, the two plants look physically different.  This is due to the different reasons that both of them are grown.  Cannabis, grown for its flowering buds for reasons of smoking or THC extraction, are generally short and wide.  Hemp, on the other hand, is tall and narrow as it is not grown for its buds. Hemp is low in THC and is often grown for a variety of purposes including the manufacture of materials.

People suffering from other neurological disorders might also benefit from using CBD oil as part of their treatment. Several studies involving Parkinson’s disease showed that participants slept better after treatment. Furthermore, their overall quality of life increased. Amazingly, CBD also showed positive benefits in treating or preventing Alzheimer’s disease. As CBD lowers inflammation, it helps prevent nerves from degenerating. During one study, scientists used mice with the genetic predisposition for Alzheimer’s disease. They found that CBD helped by preventing the mice’s cognitive decline.
[387] S. Maione, F. Piscitelli, L. Gatta, D. Vita, L. De Petrocellis, E. Palazzo, V. de Novellis, and V. Di Marzo, “Non-psychoactive Cannabinoids Modulate the Descending Pathway of Antinociception in Anaesthetized Rats through Several Mechanisms of Action,” British Journal of Phramacology 162, no. 3 (2011): 584. doi:10.1111/j.1476-5381.2010.01063.x.

Two additional studies in this area were done using CBD oil. In the first one, 214 participants would take 0.9 to 2.3 grams of oil per 1 pound of body weight. CBD successfully reduced seizures by a median of 36.5%. The second study focused on children who suffered from Dravet syndrome. Dravet syndrome is a type of epilepsy that happens in early infancy. Normally high temperatures and fevers trigger it. The results of the second study showed that CBD oil reduced seizures significantly.


A co-worker of mine recommended this product because her husband started using it and noticed more energy and significantly reduced his chronic pain symptoms almost immediatelyafter starting to use this product. She said she was able to fall asleep more easily on night one, and she woke up with energy the next morning before her alarm went off. My husband has horrible neck pain because of an accident a couple of years ago. I finally convinced him to try it out. I will update or do a new review once hes tried it out.
With hemp’s legalization, CBD is bound to become even more visible. Its legal status remains unclear — the Drug Enforcement Administration classifies CBD as illegal, although it doesn’t go after anyone using or possessing it, and it hasn’t said if it will reclassify CBD now that hemp is legal. The Food and Drug Administration still considers it a drug, and therefore categorizes it as illegal to be put in foods and or health products without its approval. After the hemp legalization bill passed, FDA Commissioner Scott Gottlieb issued a statement saying that the FDA’s opinions had not changed, and that CBD companies must obtain approval from the FDA.
For this study, 24 people with social anxiety disorder received either 600 milligrams (mg) of CBD or a placebo an hour and a half before performing a simulated public speaking test. Additionally, 12 other people with social anxiety disorder performed the same test without receiving any CBD treatment. Results revealed that pre-treatment with CBD significantly reduced anxiety, cognitive impairment, and discomfort while participants were delivering their speech.
As one of the original CBD manufacturers, Green Roads reputation truly precedes them, and their pharmacist formulated manufacturing process is why we selected them as the best quality CBD oil on the market. They offer a range of CBD oil concentrations (100mg, 250mg, 350mg, 550mg, 1000mg, 1500mg, and 3,500mg) all of which allow you to view ingredients and test results from a 3rd party testing facility via a QR code on the box.

Hemp Seed Oil is derived from the hemp seeds and are mainly used for dietary purposes (imagine something similar to coconut oil). Refined hemp seed oil can also be used in beauty care products, as they have amazing skin care properties. CBD Hemp oil is not the same thing as hemp seed oil, as it is extracted from one of hemp’s many cannabinoids and have fundamentally different properties.
The phytocannabinoid cannabidiol (CBD), is a non-intoxicating molecule that results from the heating, or decarboxylation, of cannabidiolic acid, or CBDA. As popular as CBD has become in both the cannabis community and mainstream consumerism, its natural precursor, CBDA, is one of 114 unique cannabinoids found in cannabis. In most cultivars, or cultivated varieties of cannabis, CBD ranks low on the expression chart; there often isn’t much. However, following a explosive discovery in 2009 — it was noted that a handful of strains are rich in CBD over THC. Droves of CBD-rich cultivars began cropping up all across the US, resulting in a marked uptick in CBD availability across the states.
The Cannabis Health Index (CHI) is an evidence-based scoring system for cannabis (in general, not just CBD effects) and its effectiveness on various health issues based on currently available research data. Refer to cannabishealthindex.com for updated information. Using this rubric and based on twenty-one studies, cannabis rated in the possible-to-probable range of efficacy for treatment of depression.

I have been using the 1000mg tincture and find that it is very effective at taming anxiety once I found the dosage that worked for me. I started small at 1 drop 3x per day because I had never used CBD before and found that 4 drops 3x a day is currently appropriate to get the results I am looking for. I am glad I found Medterra. Before making a CBS purchase, I did tons of research and felt that they were one of the best in the market. Customer Service response time was same day when I sent them a question.
In September 2018, following its approval by the FDA for rare types of childhood epilepsy,[13] Epidiolex was rescheduled (by the Drug Enforcement Administration) as a Schedule V drug to allow for its prescription use.[14] This change applies only to FDA-approved products containing no more than 0.1 percent THC.[14] This allows GW Pharmaceuticals to sell Epidiolex, but it does not apply broadly and all other CBD-containing products remain Schedule I drugs.[14] Epidiolex still requires rescheduling in some states before it can be prescribed in those states.[64][65]
There are two main types of receptors in the ECS, CB1 and CB2. CB1 receptors are primarily located in the central nervous system and brains of mammals, and CB2 are generally found in the peripheral nervous system. There are two main cannabinoids mammals produce- 2AG and Anandamide (named after the Sanskrit term “Ananda,” which translates to “peace”).
THC’s intoxicating powers come from its ability to mimic anandamide, an endocannabinoid or naturally occurring mood-altering substance in the body that binds to CB1 receptors in the brain and is associated with having a rosy disposition. THC binds to anandamide’s CB1 receptors even more tightly than anandamide itself, triggering an exaggerated or euphoric response — in other words, you get high.

Pure CBD cannabis oil derived from hemp contains only trace amounts of THC. Hemp is grown from specific cannabis varieties that naturally possess higher levels of CBD. These hemp stalks and hemp seeds produce organic hemp oil that is naturally rich in cannabidiol. Some genetic varieties of hemp contain higher concentrations of pure CBD than others.

CBD’s action within the brain and body is quite complicated. To date, scientists have discovered more than a dozen different mechanisms of action, or ways that CBD affect us. It’s very likely that the beneficial effects of CBD are a result of the total of its activation of all of these biological pathways, not a single one in particular. Much more research is needed to fully understand the mechanisms by which CBD relieves ailments such as anxiety and seizures.


Therefore, ingesting 2,000 mg of CBD oil daily would result in a maximum consumption of 6 mg of THC, which would cause a positive marijuana urine test approximately 23 percent of the time. It’s important to keep in mind the amount of CBD consumed. Although unlikely, it is possible for those who take CBD to fail drug tests if they are taking unusually high doses.
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The wide range of benefits associated with cannabis have garnered interest for use in cancer therapy. Research suggests that cannabinoids, including CBD, may have anti-tumor effects. While this is not enough to define cannabis as a treatment for cancer, it does make it attractive as a complement to other therapies, for both reducing symptoms and possibly enhancing the effects of anticancer drugs.
CBD oil contains CBD (and often other active compounds) in a carrier oil. There are a number of forms of CBD oil, including softgel capsules, tinctures, and under-the-tongue sprays. Some forms of CBD oil can also be applied directly to the skin, in the form of products like creams and salves. The concentration of CBD varies from product to product.
Still, CBD presents other risks for false positives. "If people are using CBD products that don't have a CoA (Certificate of Analysis) that indicates zero THC, THC could show up on a drug screen," Okel says. Availability of CBD oil has exploded, but it's not a well-regulated industry. Some oils that claim to be pure CBD have some sneaky THC in there, and that could mess up a drug test. Okel advises everyone to only purchase CBD oils with CoA purity guarantee to avoid ingesting trace amounts of THC.
CBD interacts with the body through the endogenous cannabinoid system (ECS) or endocannabinoid system. First discovered in the late 1980’s, the endocannabinoid system regulates the body’s homeostasis, or general state of balance, impacting such functions as mood, sleep, appetite, hormone regulation, and pain and immune response. Like an acrobat on a highwire, as the environment around us impacts our normal balance, the endocannabinoid system “corrects” by mediating our body’s reaction to keep us level.
Even though, thanks to the Farm Bill, hemp lost its status as a Schedule I drug – one that has no proven medical purpose and potential for abuse – marijuana did not. That means even though many states have legalized its use, the federal government still considers marijuana and CBD products derived from marijuana in almost any form to be illegal. But so far, federal law enforcement officials have not used their power to swoop in and shut down marijuana operations in states that have legalized it.
Always start with the micro dose to test sensitivity and go up as needed within the dosing range, before going to the next, until symptoms subside. The micro to standard dose is usually recommended to treat stress and anxiety with CBD. For relief of immediate symptoms, as in a panic or anxiety attack, vaporizing or smoking work well. The medication lasts one to three hours, whereas most ingested products, including CBD oil, take thirty to sixty minutes before taking effect and last six to eight hours. Vaporizers that use a cartridge filled with the CO2 concentrate are highly effective, and these are available in various ratios of CBD to THC. Herbal vaporizers that use the whole plant are also an effective delivery method. Sublingual sprays or tinctures taken as liquid drops take effect quickly and last longer than inhaled products.
THC’s intoxicating powers come from its ability to mimic anandamide, an endocannabinoid or naturally occurring mood-altering substance in the body that binds to CB1 receptors in the brain and is associated with having a rosy disposition. THC binds to anandamide’s CB1 receptors even more tightly than anandamide itself, triggering an exaggerated or euphoric response — in other words, you get high.
Compared to THC, CBD has very different properties. It weakly binds to both CB1 and CB2 receptors in the brain and body, gently stimulating and blocking them at the same time. This not only mildly activates the receptors, but is also thought to trigger the body to create more CB1 and CB2 receptors, a process known as upregulation. It also results in increased natural levels of anandamide.
The main difference between the three Original Blends is the additional herbal ingredients besides hemp. We suggest you research the separate components of each blend to determine which product may be most appealing to add to your dietary regimen. If you know it’s solely the hemp extract that you are looking for, with no additional ingredients, then Classic Hemp Blend or Classic Hemp 6x is what you’re looking for.
Cannabidiol (CBD) is a naturally-occurring constituent of industrial hemp (cannabis sativa) plants. It is the most abundant non-psychoactive cannabinoid found in cannabis and is being scientifically investigated for numerous reasons. Most people have heard of a cannabinoid called THC, which is the ingredient in cannabis that gets users high. Unlike THC, CBD (cannabidiol) is a non-psychoactive cannabinoid and does not cause a high.
Because the extraction used to make our CBD oil yields a full spectrum extract, our hemp extracts contain over 80 different phyto-cannabinoids, including CBD, CBC, CBG, CBG-A, CBC-A, and CBN, among many others. In addition to the cannabinoids naturally present in our industrial hemp extracts, there are many other types of natural molecules such as amino acids, carbohydrates, vitamins, omega fatty acids, and trace minerals. Additionally, beta-carotene, chlorophyll, flavonoids, ketones, nitrogenous compounds, alkanes, glycosides, pigments, water, and terpenes are all present in our CBD hemp. Click Here CBD
Buying CBD OIL has never been easier.  Since CBD Oil from the Hemp plant does not contain unlawful measures of THC, it is legitimate in every one of the 50 states. This is imperative to individuals everywhere throughout the US who need CBD however can’t get it locally. What’s more, legitimate CBD is accessible for home conveyance in every one of the 50 states meaning numerous individuals don’t need to move to a state with sanctioned Medical Marijuana. Additionally, in states where medicinal weed is lawful, buyers utilizing this hemp plant type of CBD don’t need to obtain a medical marijuana card.
Answering the question “what is CBD oil” would be incomplete without mentioning the many CBD oil benefits. In addition to positively affecting the endocannabinoid system, CBD has been the focus of more than 23,000 published studies about cannabinoids in relation to various medical indications including anxiety, epilepsy, inflammation, cancer and chronic pain to name few. You can even find CBD for pets that is specially formulated to safely allow your pets to experience the natural benefits of CBD. For a more comprehensive look at these and other studies, visit our medical research and education page.

Unlike with THC, CBD’s effects aren’t limited to that single receptor. These effects are not precisely known, though CBD certainly has some impact on CB1’s sister receptor (CB2) as well as a receptor called 5-HT1A. When the 5-HT1A receptor comes into contact with a material that agonizes it, the effects can include reduced anxiety and increased calmness.

I have found after trying several different brands, MedTerra is the most potent, consistent and competitively priced product on the market. Being able to purchase it by mail order is also very convenient. One thing I noticed on other brands is there seems to be confusion over the actual dosage. Folks see 500 mg on the bottle and think they are taking a 500 mg dose. Incorrect! That is the total mg CBD per bottle. One brand for example states on the 2 oz bottle, 60ml-500mg. That breaks down to 8.333mg per ml. But it was only 60% purity which translates to only 5 mg per 1 ml dose. (500mg / 60 ml = 8.3333 mg per ml, at 60 % purity 8.3333 * .6 = 5 mg per ml dose.) I have not seen anyone break it down correctly until I looked at MedTerra. They dont mess around. You get 99% pure product, period. This allows more accurate dosage than other companies, giving YOU more control and confidence using their products. Pain and inflammation greatly reduced, I sleep better, mood and blood sugar leveled out, reduced appetite. Thank you MedTerra! Word of mouth is the best advertisement! All CBD Tinctures, regardless of strength, are 1 fluid oz and contain 30 servings at 1 ml each. The dropper in the cap has measurement markers of .25, .5, .75 and 1 ml to help with serving size. Here is the breakdown by strength of the amount of CBD per serving, 1 dropper full: 500mg contains 16mg of CBD per serving 1000mg contains 33mg of CBD per serving 3000mg contains 100mg of CBD per serving
The FDA’s refusal to allow companies to market CBD as a dietary supplement is based on the fact that federal classification as a dietary supplement requires that a substance has not been authorized for investigation as a new drug or medicine. Since Epidiolex has been studied in clinical trials by GW Pharmaceuticals going back several years now and was granted orphan drug status by the FDA in 2013, CBD cannot therefore be classified as a dietary supplement. Or so the FDA says. But cannabis companies are arguing that they started marketing CBD as a dietary supplement before there were any drug trials involving CBD, such that they should still be allowed to claim dietary supplement status for their products. Thus far however, the FDA isn’t budging on this issue.  
You move fast, train hard, and recover the best that you can. Whether an athlete, government employee, or working professional that prefers the least amounts of THC in your CBD oil – our X-Oil was made with you in mind. It contains only the barest of trace amounts of THC, for ultimate confidence and effectiveness, so you can focus on performing at the top level.The first-ever CBD oil compliant with worldwide regulations brought to you by HempMeds. It’s ahead of the curve, just like you want to be.
Our supplements are derived from industrial hemp, not to be confused with marijuana. Industrial hemp is a legal plant from which many popular foods are harvested. To create our products, we extract a full spectrum of compounds from the hemp plant. This full spectrum contains a stunningly varied array of phyto-cannabinoids, including CBD, CBC, CBG, CBN, and much more. Our extracts contain less than 0.3% concentration of THC, the component from Cannabis sativa L. that causes a high.
Always start with the micro dose to test sensitivity and go up as needed within the dosing range before going to the next, until symptoms subside. The micro to standard dose is usually recommended to treat depression. Vaporized or smoked cannabis is recommended for relief of immediate symptoms, or a boost in dosage, and it can also be useful for sleep issues. Sublingual sprays or tinctures taken as liquid drops take effect quickly and last longer than inhaled products.

No. Many people are under the impression that the only way to acquire hemp extracts and CBD for themselves or a loved one is to move to Colorado or another cannabis-friendly state. Many major news outlets are misinformed and are unfortunately spreading the idea that you can only get CBD oil in the states where medical marijuana has been legalized. This is simply not the case though. Because our extracts come from hemp instead of marijuana, we can and do ship nationwide, and no medical marijuana card is needed. There are some exceptions, like with South Dakota, where we can’t sell our products due to state legislation.

We use a combination of both Subcritical and Supercritical extractions. This allows us to perform a “fractional extraction” by first extracting at lower pressures to remove the lighter, temperature-sensitive volatile oils, and then subsequently extracting the same material at a higher pressure to remove the remaining oils. This approach is the best because it allows us to extract a complete range of cannabinoids, terpenes, essential oils, and other beneficial phytochemicals that yield a more potent blend.
My husband was diagnosed with ALS (amyotrophic lateral sclerosis) when he was 61 years old 4 years ago. The Rilutek (riluzole) did very little to help him. The medical team did even less. His decline was rapid and devastating. His arms weakened first, then his hands and legs. Last year, a family friend told us about Rich Herbs Foundation (RHF) and their successful ALS TREATMENT, we visited their website www. richherbsfoundation. com and ordered their ALS/MND Formula, i am happy to report the treatment effectively treated and reversed his Amyotrophic Lateral Sclerosis (ALS), most of the symptoms stopped, he is able to walk and able to ride his treadmill again, he is pretty active now.
You then take your first drop of CBD oil, wait 45 minutes, then ask the questions again. If you feel no different and there’s no change in the way you answer those questions, you increase the dose by small increments until you do notice a difference. You can continue this process over several days – and at some point, you’ll find that taking more doesn’t change your scores. That is your minimum effective dose.
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CBD does not appear to have any psychotropic ("high") effects such as those caused by ∆9-THC in marijuana, but may have anti-anxiety and anti-psychotic effects.[9] As the legal landscape and understanding about the differences in medical cannabinoids unfolds, it will be increasingly important to distinguish "medical marijuana" (with varying degrees of psychotropic effects and deficits in executive function) – from "medical CBD therapies” which would commonly present as having a reduced or non-psychoactive side-effect profile.[9][58]
Extraction: The method by which CBD oil is processed from hemp plants can be very telling. Some manufacturers extract and process the oil using toxic materials like propane or butane; in most cases, these oils are cheaply priced. Safer extraction and processing agents include ethanol, which cleans the hemp plant of unwanted toxins; and supercritical carbon dioxide extraction, which strips harmful materials from the plant by changing the carbon dioxide’s temperature and pressure settings.
Stephanie, generally, I have patients take 20 to 150mg a day for sleep +/- anxiety. Start low and go slow. Know the dosages of your product. Usually 2/3 to 3/4 of the daily dose is 1-2 hours before bedtime, and the other portion is upon waking (to improve wakefulness during the day). Other factors such as stress, hormone replacement, other meds & medical conditions, etc. play a role along with individual differences. I own a compounding pharmacy, so we see a lot of unique needs. I can't give more specific advice in this forum, but there is help!

The vast majority of CBD oils come in bottles measuring either 15 milliliters (mL), or 0.5 ounces; or 30 mL, or 1 ounce. However, CBD concentration is more important than bottle size. Concentration refers to the ratio of hemp oil solution (measured in mL) compared to the amount of CBD cannabinoid (measured in milligrams, or mg). A 15-mL bottle may contain 100 mg of CBD, 300 mg, 500 mg, or more. The higher the mg amount, the stronger the CBD oil will be. For this reason, the ‘mg’ measurement is also referred to as the oil’s strength; i.e., 400-mg oil might be called 400-strength oil.


Cannabidiol, or CBD for short, is a natural phyto-cannabinoid (or plant-based chemical compound) found in cannabis plants, including hemp and marijuana. Unlike other cannabinoids — namely tetrahydrocannabinol, or THC — CBD does not produce any psychoactive effects, and will actually counteract these effects to a degree. CBD will induce feelings of sleepiness; for this reason, it can be an effective soporific for people who struggle to fall and/or remain asleep due to insomnia and other sleep disorders.
Hemp oil can come from the flower, leaves, stock or seeds. If it comes from the seed there are no cannabinoids found. If it comes from the rest of the plant cannabinoids are found. Hemp extract usually refers to either CBD or oil from the stock, flower, or leaves. Our Virgin cannabis sativa hemp oil is a hemp seed oil, and our Premium hemp oil products, have hemp oil from the stem of the plant (which is listed in milligrams on the bottle) It also has hemp seed oil in the bottle to act as a carrier oil. Our Hemp seed oil is a cold pressed seed oil, and our Premium hemp oil that comes from the stem is Co2 extracted.
Nature’s Script also sells a pet CBD tincture in 150mg, 300mg, and 1,000mg concentrations. As a general rule of thumb, low-concentration oils are a good option for smaller dogs while larger concentrations may be more suitable for larger breeds – but pet owners should always check with their vet beforehand. In addition to standard shipping, Nature’s Script offers expedited delivery for customers in the contiguous U.S.
CBD (Cannabidiol) is a naturally occurring compound found in the hemp plant (Cannabis Sativa). NuLeaf Naturals firmly believes that our organic CBD oil may improve the lives of individuals suffering from certain mental and physical ailments. The best of today’s science is on our side. A nonprofit called Project CBD has examined a wealth of peer-reviewed scientific research and concluded that cannabis oil may be therapeutic for individuals with conditions such as:
But Kase acknowledges that her CBD suggestions should not be confused with medical advice. Much like with her yoga instruction, she says that she is only sharing what has worked for her in the hopes that it will help others. “I don’t say, ‘I recommend and advise that you take ten drops, three times a day,’” she explained. “I say, ‘This is the particular brand that I use. You could try it and see if it helps.’ And people have told me that it does.”
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