CBD also modulates other receptors in the body. For instance, modulation of the 5-HT1A receptor (involved with serotonin, a mood hormone) provides mood-balancing properties: It’s calming, but not highly sedating, so it’s considered neutral — though it often results in improved sleep for many people. Another example is modulation of opioid receptors, which provides pain relief and tissue-supporting properties.
THC’s intoxicating powers come from its ability to mimic anandamide, an endocannabinoid or naturally occurring mood-altering substance in the body that binds to CB1 receptors in the brain and is associated with having a rosy disposition. THC binds to anandamide’s CB1 receptors even more tightly than anandamide itself, triggering an exaggerated or euphoric response — in other words, you get high.
“We’ve found that an effective dose for psychological issues, like stress anxiety, generally tends to start out at 6 mg and can go up to 20 mg,” says Zachary Clancy, a horticulturist and clinical herbalist at the Alchemist’s Kitchen, which sells a wide range of CBD goods at its retail store in lower Manhattan and also sells wholesale to restaurants. (Clinical herbalists can complete any of a variety of educational programs and apprenticeships to gain that title.)
Insomnia: The anxiety-alleviating and sleep-prolonging qualities of CBD oil make it a good option for many people with insomnia. Those who experience insomnia due to pain or discomfort may also find that using CBD oil alleviates their physical symptoms to a noticeable extent. CBD oil may also promote daytime wakefulness when taken in small amounts; people with insomnia can use it as a pick-me-up if they feel excessively tired due to lack of restful sleep.
Cannabidiol, or CBD for short, is a phyto-cannabinoid found in cannabis plants. However, it does not cause the same psychoactive effects as other naturally occurring cannabinoids (such as tetrahydrocannabinol, or THC). CBD induces feelings of sleepiness and tranquility, making it suitable for insomnia and other sleep disorders; CBD can be used to alleviate symptoms of epilepsy, diabetes, and anxiety disorders, as well. Legality is an issue for some; all 50 states have laws governing the sale, possession, and use of CBD, and they vary significantly (see the table below for a full analysis).
I have been recently diagnosed with a rare brain disease. This product helps with the debilitating headaches and the extreme nausea. My geneticist recommended this product to me. My doctor is on the cutting edge of genetic research and is highly regarded and published in several scientific journals. This product is effective and the best part is the fact that there are no side effects like other medications.
CBD oil alleviates physical pain and anxiety – both of which can have a negative impact on sleep. Additionally, CBD oil can actually prolong sleep for some, leading to more rest from night to night. Most medical experts agree that marijuana is not particularly beneficial for individuals with medical conditions and/or mental health disorders, as the THC can increase their symptoms; this makes CBD oil a good alternative option for people with the following sleep disorders and medical conditions.
Hemp Seed Oil is derived from the hemp seeds and are mainly used for dietary purposes (imagine something similar to coconut oil). Refined hemp seed oil can also be used in beauty care products, as they have amazing skin care properties. CBD Hemp oil is not the same thing as hemp seed oil, as it is extracted from one of hemp’s many cannabinoids and have fundamentally different properties.
Vapor Distillation™: Also sometimes called thermal extraction, vapor distillation uses hot air to safely vaporize the full spectrum of chemical components at high concentration from the buds, and then the vapor is distilled into CBD oil. This method also activates the cannabinoids by removing an extra carboxyl ring from their molecular chain (a chemical reaction called decarboxylation), enabling them to interact directly with CB receptors for maximal medicinal value.
The wide range of benefits associated with cannabis have garnered interest for use in cancer therapy. Research suggests that cannabinoids, including CBD, may have anti-tumor effects. While this is not enough to define cannabis as a treatment for cancer, it does make it attractive as a complement to other therapies, for both reducing symptoms and possibly enhancing the effects of anticancer drugs.
I have suffered from Neuropathy to both feet for about six years. The symptoms are numbness and pins and needs to the metatarsal region as well as the toes. There is also an intermittent very intense internal itching to the soles of both feet, which changes in location. I have been offered painkilling prescription drugs, but have refused these. I am very interested to learn of the benefits of Hemp/CBD Oil, and would appreciate some advice on which product you feel would most benefit my condition. Many thanks for your anticipated assistance. You may wish to reply to me by e-mail.
Third party laboratories analyze all of our full-spectrum hemp extracts and supplements for cannabinoid potency, heavy metals, bacterial/microbial life, mycotoxins (fungus), and pesticides. Our isolate is tested for potency, heavy metals, and pesticides. The unsummarized results of testing for all produced batches can be found in our online batch database.
For legal reason I can’t make any claims that our product will treat or cure your neuropathy or any other medical diagnosis. However, If you do your research on google you may find a tie between full spectrum hemp oil and Neuropathy. Our product is great for assisting with pain, inflammation and stress. If you are feeling pain or experiencing inflammation you should try our product. Now if you have serious pain I would suggest our premium hemp oil drops at 5x strength.
Recent testing of cannabis products from Los Angeles marijuana dispensaries showed over 90% of tested products to contain HIGHER than normal contaminants and pesticide levels, despite organic claims. (The USDA National Organic Program does not certify organic claims on marijuana, and it’s actually not a legally permitted claim on these products.- FYI, I’m an certified IOIA, Independent Organic Inspectors Association organic processing inspector.) There’s no intrinsic difference between high-THC cannabis and low-THC cannabis that somehow renders one clean and one heavy with contaminants. As with every other crop, it is a matter of soil conditions, growing conditions and horticultural inputs.
People: CBD oil is kind of similar (not 100% similar) to pharmaceuticals in which it can have many different reactions in each person. A pharma drug may be a psychotic, but in some people they use it for sleep, and others it makes them wired. You know the 4-6 pages you get with a pharma drug to tell you all of the potential BAD side effects? Well this is the same for CBD oil but it’s GOOD side effects. No company selling CBD will know how it affects you body. This INDUSTRY is NEW. They have no studies and no research. SO, try different ones and it is YOUR RESPONSIBILITY to do research and TRIAL it. AND the good news is there are VERY FEW bad side effects. We have to say that, even though i have not seen anyone have side effects, start low and increase based on how YOUR BODY reacts to is. AGAIN, it’s a natural plant that has ZERO fatalities as opposed to a pharma drug that has 2-6 pages of potential side effects, and MOST people get a few like weight gain, a rash, getting high (can’t drive), drowziness and then a whole host of life threatening side effects. I’m pretty sure 100% of you have taken a pharma drug without all of the questions you are asking about CBD. Yes, it’s true there is no doctor to direct you, but come on, there are really no bad side effects so do your own due diligence. Anyone who tells you they know what you need in CBD oil is lying.
Cannabidiol—CBD—is a cannabis compound that has significant medical benefits, but does not make people feel “stoned” and can actually counteract the psychoactivity of THC. The fact that CBD-rich cannabis is non-psychoactive or less psychoactive than THC-dominant strains makes it an appealing option for patients looking for relief from inflammation, pain, anxiety, psychosis, seizures, spasms, and other conditions without disconcerting feelings of lethargy or dysphoria.
CBD oil contains CBD (and often other active compounds) in a carrier oil. There are a number of forms of CBD oil, including softgel capsules, tinctures, and under-the-tongue sprays. Some forms of CBD oil can also be applied directly to the skin, in the form of products like creams and salves. The concentration of CBD varies from product to product.
A 2013 study that measured data from 4,652 participants on the effect of cannabis on metabolic systems compared non-users to current and former users. It found that current users had higher blood levels of high-density lipoprotein (HDL-C) or “good cholesterol.” The same year, an analysis of over seven hundred members of Canada’s Inuit community found that, on average, regular cannabis users had increased levels of HDL-C and slightly lower levels of LDL-C (“bad cholesterol”).
Choosing CBD products isn’t as simple as picking something off the dispensary shelf and then walking out the door. Consumers should be aware that a handful of hemp products on the market pay lip service to governmental regulations by labeling themselves as hemp, despite containing cannabinoids and terpenoids. Some CBD products are completely devoid of cannabinoids including CBD, despite package labeling. The FDA purchased a number of CBD products online in 2015 and 2016 to test them for the presence of CBD and other cannabinoids. They found that the amount of CBD these products claimed on their labels was markedly inaccurate; some didn’t even contain CBD.
One of CBD’s chief properties is its anticonvulsant nature. Clinical trials have shown that CBD is effective at reducing seizures in children, and the FDA is likely to approve Epidiolex, a pharmaceutical-grade version of CBD for this use, in summer 2018. Although CBD has been documented as an antiepileptic since 1881, CBD’s anticonvulsant mechanisms still remain unclear. Not enough studies have been conducted to understand this relationship fully. One possible explanation for CBD’s neuroprotective effects is its interaction with NMDA receptors, which play a key role in the overly active neuron activity that is a hallmark of epilepsy.
These products are from places like Xi’an Lyphar Biotech Co. Ltd., which doesn’t mention that it’s one of the largest CBD sellers on Alibaba on its website, let alone reveal where it’s sourcing its CBD from. There are big companies and small companies, companies that provide elaborate chemical charts and companies that have no online presence at all. There are companies that run their goods — either as raw materials or as consumer-stage final products — through lab tests. There are those that say they do but provide no information on what the labs found or which labs tested their products.
As mentioned previously, while CBD-dominant products help some people sleep, in others it promotes wakefulness. Orally administered THC, especially products from heavier “Kush” strains and Purple cannabis varieties, are very effective for sleep disorders. These tend to be high in myrcene and linalool, a terpene shared with lavender and known to be effective for relaxation. Cannabis combinations with ratios of 1:1, 4:1, or 24:1 CBD:THC can be used when patients want to reduce psychoactivity.
Industrial hemp contains, by weight, far less CBD than CBD-rich cultivars such as Harlequin or Sour Tsunami. This means that producing a single 10 mL dose of CBD would require the cultivation and extraction of far more hemp than it would from whole-plant marijuana; thus raising the risk of exposing users to more contaminants. Hemp is classified as a “bioaccumulator,” or a plant that naturally absorbs toxicants from the soil.
Cooper recently got funding from the National Institutes of Health for a study looking at cannabinoids — including CBD in isolation — as a substitute for opioids, and numerous other clinical trials of CBD are underway. It will be several years before results are available, but these studies should help clarify both what benefits the substance may provide and any side effects it may come with. Most of the adverse effects so far associated with cannabis, such as impairments in short-term memory, coordination and judgment,2 come from products that contain THC as well as CBD, Cooper said, but we need to do more studies to find out for sure whether CBD has fewer risks. Studies are also needed to identify the best way to administer and dose CBD. “I get emails from people asking me what dose of CBD to use, and the truth is, we really don’t know,” Cooper said.
Answering the question “what is CBD oil” would be incomplete without mentioning the many CBD oil benefits. In addition to positively affecting the endocannabinoid system, CBD has been the focus of more than 23,000 published studies about cannabinoids in relation to various medical indications including anxiety, epilepsy, inflammation, cancer and chronic pain to name few. You can even find CBD for pets that is specially formulated to safely allow your pets to experience the natural benefits of CBD. For a more comprehensive look at these and other studies, visit our medical research and education page.